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Chapter DP-33

DES as a Potent Green Solvent and Catalyst for the Synthesis of Biologically Active Pyrimidinethiones

Harsh Pahuja, Prarthana Rohtagi, Dr. K. Murali Mohan Achari, Prof. Sharda Pasricha

Abstract

Synthesis of 4,6-diaryl-3,4-dihydropyrimidine-2(1H)-thiones using biodegradable deep eutectic solvent (DES) with yields ranging from 45-99%. Protocol involves simple work-up procedure without column chromatography.

Keywords: Dihydropyrimidine-2(1H)-thiones; Chalcones; Green chemistry; Deep eutectic solvent

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